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| Upper Austria Ladies Linz | ||
| Surface: Hard | Date: Nov. 7 - Nov. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jasmine Paolini | Loss | 4-6, 6-3, 2-6 |
| Courmayeur Ladies Open 2021 | ||
| Surface: Hard | Date: Oct. 25 - Oct. 31 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Vitalia Diatchenko | Win | 6-3, 6-1 |
| Second Round | Kateryna Kozlova | Win | 6-1, 3-6, 7-5 |
| Quarterfinals | Jasmine Paolini | Loss | 4-6, 6-7 (4-7) |
| VTB Kremlin Cup | ||
| Surface: Hard | Date: Oct. 18 - Oct. 24 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Anna Kalinskaya | Loss | 6-7 (5-7), 4-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Oct. 6 - Oct. 17 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Elsa Jacquemot | Win | 6-2, 6-4 |
| Second Round | Paula Badosa | Loss | 4-6, 6-2, 2-6 |
| Chicago Fall Tennis Classic | ||
| Surface: Hard | Date: Sep. 27 - Oct. 3 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Alize Cornet | Win | 7-5, 6-1 |
| Second Round | Elise Mertens | Loss | 1-6, 3-6 |
| Zavarovalnica Sava Portoroz | ||
| Surface: Hard | Date: Sep. 13 - Sep. 19 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Jasmine Paolini | Loss | 6-7 (5-7), 1-4 Retired |
| US Open | ||
| Surface: Hard | Date: Aug. 30 - Sep. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Angelique Kerber | Loss | 6-3, 4-6, 6-7 (3-7) |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 15 - Aug. 22 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Catherine McNally | Win | 7-6 (7-3), 7-6 (7-1) |
| Second Round | Barbora Krejcikova | Loss | 1-6, 6-7 (5-7) |
| National Bank Open presented by Rogers | ||
| Surface: Hard | Date: Aug. 9 - Aug. 15 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Sloane Stephens | Loss | 4-6, 6-1, 4-6 |
| Mubadala Silicon Valley Classic | ||
| Surface: Hard | Date: Aug. 2 - Aug. 8 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Claire Liu | Loss | 3-6, 6-4, 4-6 |
| Women's Hamburg European Open | ||
| Surface: Red Clay | Date: Jul. 6 - Jul. 11 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Magdalena Frech | Win | 7-6 (7-5), 6-1 |
| Quarterfinals | Sara Errani | Win | 7-6 (7-4), 6-4 |
| Semifinals | Elena-Gabriela Ruse | Loss | 6-2, 1-6, 4-6 |
