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| Transylvania Open | ||
| Surface: Clay | Date: Oct. 25 - Oct. 31 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Andrea Petkovic | Win | 6-4, 2-6, 6-4 |
| Second Round | Simona Halep | Loss | 4-6, 2-6 |
| Tenerife Ladies Open | ||
| Surface: Hard | Date: Oct. 18 - Oct. 24 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Sara Sorribes Tormo | Win | 6-4, 5-7, 7-6 (7-4) |
| Second Round | Ann Li | Loss | 4-6, 2-6 |
| J&T Banka Ostrava Open 2021 | ||
| Surface: Hard | Date: Sep. 20 - Sep. 26 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Paula Badosa | Loss | 2-6, 2-6 |
| Astana Open | ||
| Surface: Hard | Date: Sep. 20 - Oct. 2 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Kristyna Pliskova | Win | 6-3, 7-6 (7-5) |
| Second Round | Lesia Tsurenko | Win | 6-2, 6-4 |
| Quarterfinals | Alison Van Uytvanck | Loss | 4-6, 4-6 |
| BGL BNP Paribas Luxembourg Open | ||
| Surface: Hard | Date: Sep. 13 - Sep. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Mandy Minella | Loss | 3-6, 4-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 30 - Sep. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Nuria Parrizas-Diaz | Win | 5-7, 6-0, 6-2 |
| Second Round | Paula Badosa | Win | 6-4, 6-4 |
| Third Round | Anastasia Pavlyuchenkova | Loss | 1-6, 4-6 |
| Chicago Women's Open | ||
| Surface: Hard | Date: Aug. 22 - Aug. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Tamara Zidansek | Win | 6-3, 1-6, 6-2 |
| Second Round | Ana Bogdan | Win | 7-5, 3-1 Retired |
| Quarterfinals | Marta Kostyuk | Win | 6-7 (4-7), 6-3, 6-4 |
| Semifinals | Alize Cornet | Loss | 6-4, 1-6, 0-6 |
| Gdynia Open | ||
| Surface: Clay | Date: Jul. 19 - Jul. 25 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Viktoria Kuzmova | Loss | 4-6, 7-6 (7-4), 5-7 |
| Ladies Championship Lausanne | ||
| Surface: Clay | Date: Jul. 12 - Jul. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Mandy Minella | Loss | 3-6, 2-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jun. 28 - Jul. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Petra Martic | Loss | 7-6 (7-3), 4-6, 3-6 |
| Bad Homburg Open | ||
| Surface: Grass | Date: Jun. 20 - Jun. 26 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Katerina Siniakova | Loss | 3-6, 2-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 30 - Jun. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Lara Arruabarrena | Win | 6-2, 6-3 |
| Second Round | Camila Giorgi | Win | 7-5, 1-6, 6-2 |
| Third Round | Marta Kostyuk | Loss | 1-6, 2-6 |
| Internationaux de Strasbourg | ||
| Surface: Clay | Date: May 23 - May 29 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Clara Burel | Loss | 3-6, 1-6 |
| Emilia-Romagna Open | ||
| Surface: Clay | Date: May 17 - May 29 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Petra Martic | Loss | 4-6, 2-6 |
| Volvo Car Open | ||
| Surface: Green Clay | Date: Apr. 5 - Apr. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Paula Badosa | Loss | 6-3, 5-7, 1-6 |
| Abierto GNP Seguros | ||
| Surface: Hard | Date: Mar. 15 - Mar. 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Saisai Zheng | Loss | 3-6, 5-7 |
| Abierto de Guadalajara | ||
| Surface: Hard | Date: Mar. 8 - Mar. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Danka Kovinic | Loss | 6-3, 4-6, 5-7 |
| Open 6eme Sens | ||
| Surface: Hard | Date: Mar. 1 - Mar. 7 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Timea Babos | Loss | 4-6, 7-5, 3-6 |
| Phillip Island Trophy | ||
| Surface: Hard | Date: Feb. 13 - Feb. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Sloane Stephens | Win | 6-2, 6-2 |
| Second Round | Daria Kasatkina | Loss | 4-6, 3-6 |
| Australian Open | ||
| Surface: Hard | Date: Feb. 8 - Feb. 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Anna Blinkova | Win | 6-1, 3-6, 7-6 (10-7) |
| Second Round | Veronika Kudermetova | Loss | 7-5, 2-6, 2-6 |
| Yarra Valley Classic | ||
| Surface: Hard | Date: Jan. 31 - Feb. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Lizette Cabrera | Win | 2-6, 6-4, 6-2 |
| Second Round | Marketa Vondrousova | Loss | 4-6, 0-6 |
