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| US Open | ||
| Surface: Hard | Date: Aug. 29 - Sep. 11 | Seed: 15 |
| Round | Opponent | W / L | Result |
| First Round | Maximilian Marterer | Win | 6-3, 6-2, 7-5 |
| Second Round | Albert Ramos-Vinolas | Win | 6-3, 7-6 (7-4), 6-3 |
| Third Round | Daniel Evans | Win | 7-6 (13-11), 6-7 (3-7), 6-2, 7-5 |
| Fourth Round | Carlos Alcaraz | Loss | 4-6, 6-3, 4-6, 6-4, 3-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 14 - Aug. 21 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Jaume Munar | Win | |
| Second Round | Emil Ruusuvuori | Win | |
| Third Round | Carlos Alcaraz | Loss |
| Open de la Banque Nationale presentee par Rogers | ||
| Surface: Hard | Date: Aug. 8 - Aug. 14 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Borna Coric | Win | |
| Second Round | Karen Khachanov | Win | |
| Third Round | Tommy Paul | Loss |
| cinch Championships | ||
| Surface: Grass | Date: Jun. 13 - Jun. 19 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Liam Broady | Win | |
| Second Round | Alexander Bublik | Win | |
| Quarterfinals | Emil Ruusuvuori | Win | |
| Semifinals | Filip Krajinovic | Loss |
| Roland Garros | ||
| Surface: Red Clay | Date: May 22 - Jun. 5 | Seed: 20 |
| Round | Opponent | W / L | Result |
| First Round | Attila Balazs | Win | |
| Second Round | Marton Fucsovics | Win | |
| Third Round | Gilles Simon | Win | |
| Fourth Round | Daniil Medvedev | Win | |
| Quarterfinals | Andrey Rublev | Win | |
| Semifinals | Casper Ruud | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 8 - May 15 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Matteo Arnaldi | Win | |
| Second Round | Cameron Norrie | Win | |
| Third Round | Cristian Garin | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 28 - May 8 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Albert Ramos-Vinolas | Win | |
| Second Round | Alexander Zverev | Loss |
| Millennium Estoril Open | ||
| Surface: Red Clay | Date: Apr. 25 - May 1 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Sebastian Baez | Loss |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 10 - Apr. 17 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jo-Wilfried Tsonga | Win | |
| Second Round | Taylor Fritz | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 3 | Seed: 21 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Alexei Popyrin | Win | |
| Third Round | Carlos Alcaraz | Loss |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 9 - Mar. 20 | Seed: 24 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Miomir Kecmanovic | Loss |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 21 - Feb. 26 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jiri Vesely | Loss |
| Qatar ExxonMobil Open | ||
| Surface: Hard | Date: Feb. 14 - Feb. 19 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Botic van de Zandschulp | Win | |
| Quarterfinals | Karen Khachanov | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 17 - Jan. 30 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | Emilio Gomez | Win | |
| Second Round | Norbert Gombos | Win | |
| Third Round | Andrey Rublev | Win | |
| Fourth Round | Felix Auger-Aliassime | Loss |
| Adelaide International 2 | ||
| Surface: Hard | Date: Jan. 10 - Jan. 15 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jaume Munar | Win | |
| Quarterfinals | Tommy Paul | Win | |
| Semifinals | Thanasi Kokkinakis | Loss |
| Adelaide International 1 | ||
| Surface: Hard | Date: Jan. 3 - Jan. 9 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Thiago Monteiro | Win | |
| Quarterfinals | Laslo Djere | Win | |
| Semifinals | Karen Khachanov | Loss |
