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| Rolex Shanghai Masters | ||
| Surface: Hard | Date: Oct. 4 - Oct. 15 | Seed: 28 |
| Round | Opponent | W / L | Result |
| First Round | Bye |
| China Open | ||
| Surface: Hard | Date: Sep. 28 - Oct. 4 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Lloyd Harris | Win | 6-7 (5-7), 7-6 (7-4), 6-3 |
| Second Round | Casper Ruud | Loss | 6-1, 5-7, 6-7 (7-9) |
| Zhuhai Championships | ||
| Surface: Hard | Date: Sep. 20 - Sep. 26 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Luke Saville | Win | 6-4, 6-4 |
| Second Round | Dalibor Svrcina | Win | 6-2, 6-3 |
| Quarterfinals | Sebastian Korda | Loss | 1-6, 2-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 28 - Sep. 10 | Seed: 30 |
| Round | Opponent | W / L | Result |
| First Round | Otto Virtanen | Win | 6-3, 6-7 (3-7), 1-6, 6-4, 7-6 (10-5) |
| Second Round | Stan Wawrinka | Loss | 6-7 (6-8), 7-6 (9-7), 3-6, 2-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 13 - Aug. 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Alejandro Davidovich Fokina | Loss | 3-6, 3-6 |
| Omnium National Bank presented by Rogers | ||
| Surface: Hard | Date: Aug. 7 - Aug. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Sebastian Korda | Loss | 3-6, 2-6 |
| Generali Open | ||
| Surface: Red Clay | Date: Jul. 31 - Aug. 5 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Guido Andreozzi | Win | 6-2, 6-2 |
| Quarterfinals | Daniel Elahi Galan | Win | 6-7 (6-8), 6-3, 6-4 |
| Semifinals | Sebastian Baez | Loss | 6-7 (5-7), 6-3, 4-6 |
| Hamburg European Open | ||
| Surface: Red Clay | Date: Jul. 24 - Jul. 30 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Laslo Djere | Loss | 6-7 (2-7), 3-6 |
| Nordea Open | ||
| Surface: Clay | Date: Jul. 17 - Jul. 23 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Sebastian Ofner | Loss |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 3 - Jul. 16 | Seed: 29 |
| Round | Opponent | W / L | Result |
| First Round | Bernabe Zapata Miralles | Win | |
| Second Round | Stan Wawrinka | Loss |
| Rothesay International Eastbourne | ||
| Surface: Grass | Date: Jun. 26 - Jul. 1 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | J.J. Wolf | Loss |
| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jack Draper | Win | |
| Second Round | Alex De Minaur | Win | |
| Third Round | Borna Coric | Win | |
| Fourth Round | Yoshihito Nishioka | Win | |
| Quarterfinals | Alexander Zverev | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 10 - May 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Luca Van Assche | Win | |
| Second Round | Novak Djokovic | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 26 - May 7 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Adrian Mannarino | Win | |
| Second Round | Frances Tiafoe | Loss |
| Barcelona Open Banc Sabadell | ||
| Surface: Clay | Date: Apr. 17 - Apr. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Pablo Andujar | Win | |
| Second Round | Alejandro Davidovich Fokina | Loss |
| Fayez Sarofim & Co. U.S. Men's Clay Court Championship | ||
| Surface: Clay | Date: Apr. 3 - Apr. 9 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Juan Manuel Cerundolo | Win | |
| Second Round | Max Purcell | Win | |
| Quarterfinals | Cristian Garin | Win | |
| Semifinals | Yannick Hanfmann | Win | |
| Final | Frances Tiafoe | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 2 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Pavel Kotov | Win | |
| Second Round | Karen Khachanov | Loss |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Andy Murray | Loss |
| Chile Dove Men+Care Open | ||
| Surface: Clay | Date: Feb. 27 - Mar. 5 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Fabio Fognini | Win | |
| Second Round | Francisco Cerundolo | Win | |
| Quarterfinals | Dusan Lajovic | Win | |
| Semifinals | Sebastian Baez | Win | |
| Final | Nicolas Jarry | Loss |
| Rio Open presented by Claro | ||
| Surface: Clay | Date: Feb. 20 - Feb. 26 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Albert Ramos-Vinolas | Loss |
| Argentina Open | ||
| Surface: Clay | Date: Feb. 13 - Feb. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Hugo Dellien | Win | |
| Second Round | Roberto Carballes Baena | Win | |
| Quarterfinals | Cameron Norrie | Loss |
| Cordoba Open | ||
| Surface: Clay | Date: Feb. 6 - Feb. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Joao Sousa | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 29 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Gregoire Barrere | Win | |
| Second Round | Jannik Sinner | Loss |
| Adelaide International 2 | ||
| Surface: Hard | Date: Jan. 9 - Jan. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jason Kubler | Loss |
