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| Chengdu Open | ||
| Surface: Hard | Date: Sep. 20 - Sep. 26 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Benjamin Lock | Win | 6-2, 6-3 |
| Second Round | Corentin Moutet | Win | 6-2, 6-4 |
| Quarterfinals | Alexander Zverev |
| US Open | ||
| Surface: Hard | Date: Aug. 28 - Sep. 10 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Juan Pablo Varillas | Loss | 6-1, 5-7, 5-7, 4-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 13 - Aug. 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Tommy Paul | Loss | 5-7, 6-7 (2-7) |
| Omnium National Bank presented by Rogers | ||
| Surface: Hard | Date: Aug. 7 - Aug. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Cristian Garin | Win | 7-6 (7-2), 4-6, 6-4 |
| Second Round | Hubert Hurkacz | Loss | 7-5, 3-6, 0-6 |
| Hamburg European Open | ||
| Surface: Red Clay | Date: Jul. 24 - Jul. 30 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Dusan Lajovic | Loss | 6-3, 4-6, 3-6 |
| EFG Swiss Open Gstaad | ||
| Surface: Clay | Date: Jul. 17 - Jul. 23 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Dominic Stricker | Win | |
| Quarterfinals | Zizou Bergs | Win | |
| Semifinals | Albert Ramos-Vinolas | Loss |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 3 - Jul. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Diego Schwartzman | Loss |
| Rothesay International Eastbourne | ||
| Surface: Grass | Date: Jun. 26 - Jul. 1 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Yibing Wu | Win | |
| Second Round | Aleksandar Vukic | Win | |
| Quarterfinals | Gregoire Barrere | Loss |
| Cinch Championships | ||
| Surface: Grass | Date: Jun. 19 - Jun. 25 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Cameron Norrie | Loss |
| Libema Open | ||
| Surface: Grass | Date: Jun. 12 - Jun. 18 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Milos Raonic | Loss |
| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 11 | Seed: 31 |
| Round | Opponent | W / L | Result |
| First Round | Andrea Vavassori | Loss |
| Open Parc Auvergne-Rhone-Alpes Lyon | ||
| Surface: Clay | Date: May 21 - May 27 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Oriol Roca-Batalla | Win | |
| Second Round | Jack Draper | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 10 - May 21 | Seed: 30 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Fabio Fognini | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 26 - May 7 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Cristian Garin | Loss |
| Banja Luka Open | ||
| Surface: Clay | Date: Apr. 17 - Apr. 23 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Abdullah Shelbayh | Win | |
| Quarterfinals | Jiri Lehecka | Win | |
| Semifinals | Dusan Lajovic | Loss |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 9 - Apr. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Lorenzo Musetti | Loss |
| Millennium Estoril Open | ||
| Surface: Red Clay | Date: Apr. 3 - Apr. 9 | Seed: 6 |
| Round | Opponent | W / L | Result |
| Second Round | Jurij Rodionov | Win | |
| Quarterfinals | Bernabe Zapata Miralles | Win | |
| Semifinals | Marco Cecchinato | Win | |
| Final | Casper Ruud | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 2 | Seed: 29 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ugo Humbert | Win | |
| Third Round | Andrey Rublev | Loss |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: 26 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Stan Wawrinka | Loss |
| Abierto Mexicano Telcel presentado por HSBC | ||
| Surface: Hard | Date: Feb. 26 - Mar. 4 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Denis Shapovalov | Loss |
| Delray Beach Open | ||
| Surface: Hard | Date: Feb. 13 - Feb. 19 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Nuno Borges | Win | |
| Quarterfinals | Marcos Giron | Win | |
| Semifinals | Radu Albot | Win | |
| Final | Taylor Fritz | Loss |
| Dallas Open | ||
| Surface: Hard | Date: Feb. 6 - Feb. 12 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Emilio Gomez | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 29 | Seed: 26 |
| Round | Opponent | W / L | Result |
| First Round | Nicolas Jarry | Loss |
| Adelaide International 2 | ||
| Surface: Hard | Date: Jan. 9 - Jan. 14 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Kyle Edmund | Win | |
| Second Round | Jason Kubler | Win | |
| Quarterfinals | Thanasi Kokkinakis | Loss |
| Adelaide International 1 | ||
| Surface: Hard | Date: Jan. 1 - Jan. 8 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Christopher O'Connell | Win | |
| Second Round | Daniil Medvedev | Loss |
